Ephedra Diet Pills Available; Ephedra alkaloids in Diet Pills

Lipodrene ephedra diet pills sales are droping. Why would thqat happen, you say? Because Lipodrene and the other products made by Hi-Tech Pharmaceuticals use "ephedra leaves". The problem with ephedra leaves is that they do not contain any ephedra alkaloids and therefore can not work the way ephedra products like Metabadrine do because they contain ephedra extract with ephedra alkaloids.

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Buy ephedra diet pills for a very short time - ephedra products like Metabadrine
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Ephedra alkaloids in Diet Pills

Ephedrine acts as a stimulant in the central nervous system. Of the ephedra alkaloids, ephedrine is the most potent thermogenic agent. Milder thermogenic agents such as green tea and cayenne pepper, which can be taken as a premeal beverage or supplement are available and are often combined with ephedra. It may function as an anorectic by acting on the satiety center in the hypothalamus.
According to NIH government web site, the Chinese botanical ephedra, or ma-huang, is sold as a dietary supplement in the United States. Ephedra is the common name for three principal species: Ephedra sinica, Ephedra equisentina, and Ephedra intermedia. The active compounds in the plant's stem (about 1.32% by weight) are the phenylalanine-derived alkaloids ephedrine, pseudoephedrine, phenylpropanolamine (norephedrine), and cathine (norpseudoephedrine). That is why the new products made by Hi-Tech can not work.
Ephedra alkaloid content and composition vary by species and growth conditions; total alkaloid content can vary from 0.5% to 2.3%. Ephedrine, the most potent alkaloid and the same as found in the origional Metabadrine, can account for up to 90% of the total alkaloid content and pseudoephedrine can account for up to 27%. The pharmacologic activity of an ephedra sample depends on its alkaloid composition. North American ephedra species, such as E. nevadensis (known as Mormon tea), contain little or no ephedrine or other alkaloids.
Ephedrine is a mixed sympathomimetic agent that enhances the release of norepinephrine from sympathetic neurons and stimulates alpha and beta receptors. Ephedrine stimulates heart rate, thereby increasing cardiac output. It causes peripheral constriction resulting in an increase in peripheral resistance that can lead to a sustained rise in blood pressure. It relaxes bronchial smooth muscle and is used as a decongestant and for temporary relief of shortness of breath caused by asthma.
Obesity, defined as Body Mass Index (BMI) greather than 30 kg/m2 , is a widespread problem in the U.S. and a major public health concern. One-third of Americans, up from 25 percent as recently as 1980, are obese, according to statistics gathered by the National Institute of Health. This dramatic rise in such as short time paints in alarming picture of the rapidly mounting threat obesity poses to our national health.1 Obesity increases the risk of severe chronic illnesses, most notably heart disease, cancer and diabetes, and is associated with reduced longevity. Over 300,000 people die in the U.S. each year because of obesity.2 Nearly six percent of all the total health care costs in this country—about 52 billion dollars—is attributable to obesity.3
Effective solutions to obesity and overweight (BMI:25-30 kg/m2) are urgently needed. Commercial diet programs, accounting for more than a billion dollars spent annually by Americans at weight-loss centers, have a poor track record. It is estimated that 80 million Americans begin dieting each year, only gain back 95 percent of lost weight within five years.4 Fed up with the vicious circle of crash dieting, consumers are turning to natural approaches which can help manage weight by supporting, normal metabolic functions that burn fat and build lean muscle. In addition, normalizing blood glucose levels is a key element of healthy, long-term weight management program.
The use of thermogenic agents, popularly known as “thermogenics,” has become a popular strategy for managing body weight. Thermogenics is the metabolic production of heat through burning of calories consumed in food. Thermogenics stimulate metabolism to increase coloric burning. This contrasts with calorie-cutting diet plans, which can cause the body to compensate by slowing metabolism, with the end result of gaining back lost weight once a normal diet is resumed.
Supporting thermogenises is now seen as a far more effective strategy for long-term weight loss. Herbal thermogenics such as ephedra, while effecticve, contain alkaloids that can have undesirable side effects on the nervous and cardiovascular systems.5 Alternatives are available such as Citrus aurantium that can increase thermogenises with less unwanted side effects.
Citrus aurantium
Citrus aurantium, the unripe fruit of the Bitter Orange tree, is used in traditional Chinese medicine for relief of indigestion, abdominal pain, gas, constipation and chest congestion. the immature peel of citrus aurantium contains alkaloids including synephrine, tyramine and octopamine. Citrus aurantium extracts have demonstrated antiobesity effects in rat, reportedly mediated by primarily synephrine.
Every cell in the body has cell receptors that are acted upon by various compounds to trigger cellular responses. Two types of receptors in particular, “alpha” and “beta” receptors are involved in thermogenesis. Activation of these receptors also stimulates various cardiovascular respondes, including blood pressure changes due to constriction and dilation of blood vessels in the hear and skeletal muscle. This is why stimulant herbs, notably Ephedra, have the aforementioned side-effects. One receptor type, called “beta-3” increases thermogenesis (production of heat through burning of calories) and lipolysis (breakdown of fat) without the cardiovascular effects. The ideal weight loss agent would stimulate only the beta-3 receptors, with little or no effect on alpha receptors. Questions about the safety of ephedra has led to the search for milder alternatives with fewer side-effects. Data from recent studies suggests that Citrus aurantium is one such alternative.
Pure synephrine and octopamine have been shown to stimulate alpha receptors in the test tube, but their effect is fairly weak. In a preliminary study at McGill University, seven lean healthy subjects consumed a mixture of alkaloids from Citru aurantium. Results showed increased thermogenesis, with no measurable cardiovascular side-effects.9 A patent-pending Citrus aurantium extract containing a unique mixture of total amines is reported to stimulate thermogenesis and lipolysis as effectively as ephedra alkaloids, with little or no cardiovascular effect. Called Advantra Z™, this extract is believed to act primarily on the advantageous beta-3 receptors while leaving the alpha receptors for the most part alone.
Metabadrine contains real ephedra alkaloids and cutrus aurantium.